![]() ![]() "There was some very important help given by the Electronic Frontier Foundation, and we ended up scheduling a conversation with Apple, and after a while Apple was very gracious and understanding,” he said. According to the app's developer, who spoke to The Verge, the issues with Apple have been resolved. Along with an iOS app, Cryptocat is also available for the Mac and as a browser extension for Chrome, Firefox, and Safari.Ĭryptocat was originally announced for iOS in December, but the app was initially rejected by Apple, a decision that has since been reversed. There are also no buddy lists or account history, making conversations ephemeral.Īccording to the developers, Cryptocat is a native iPhone application that uses iOS APIs rather than web cryptography, but it is designed to work seamlessly with other Cryptocat clients. ![]() Unlike other secure chat apps, including Confide, Cryptocat does not require usernames, email addresses, or accounts to use, with users entering a one-time nickname to chat. Cryptocat is free, open chat that aims to provide an open, accessible Instant Messaging environment with a transparent layer of encryption that's easy to use. Designed to allow secure online chatting, the app encrypts chat messages to allow users to have single and group conversations that are secure and unable to be intercepted or monitored.Įveryone's favourite privacy-loving cat is now on iPhone! Get an encrypted cat in your pocket, have private chats with friends any time.Įasily have group conversations with your friends without fearing monitoring or interception. Open source web and Mac application Cryptocat is now available on iOS. ![]()
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![]() ![]() High sensitivity is also required to detect the rare clones within the repertoire. High enough throughput is required to be able to identify all the genetic rearrangements that make up the immune repertoire. Identifying methods to monitor and speed up the recovery of the immune repertoire would also be beneficial.Īccurately determining the immune repertoire is challenging on several fronts. imAEs are also called immune-related adverse events (irAEs) and measuring the immune repertoire may help indicate if a patient will have a greater propensity for them. Immune-mediated adverse events (imAEs) are indeed one of the limiting factors for development of cancer treatments, resulting in patients needing to be nursed back to health in carefully monitored environments. Treatments are also in development to increase the immune repertoire, such as the use of cytokines as drugs.Ī low immune repertoire after therapy, such as cancer treatment, may be a potential side effect of treatment, indicating a weakening of the immune system and resulting greater susceptibility to disease. Measuring the immune repertoire may help to predict therapeutic outcome and be used to monitor the effects of treatment. Numerous treatments are in development and coming into use that affect the immune system. Understanding the immune repertoire is important with the advent of precision medicine and immunotherapy, where treatments are being developed that are tailored to an individual for greater efficacy. In the immune repertoire, only lymphocytes that encounter an antigen with the right receptor to bind to it will be activated and proliferate during an immune response, forming a clone of cells with identical antigen receptors. ![]() According to natural selection, organisms that are better suited for an environment thrive and produce offspring. Since T-cell and B-cell lymphocytes are constantly monitoring the body for antigens from foreign bodies, they undergo a process similar to natural selection. At any given point in time, a person’s immune repertoire is made up of ~10 8 lymphocytes with different specificities (1).Įach mature lymphocyte differs from the others in the repertoire in its specificity, and it is ‘clonal’. Researchers also refer to the TCR repertoire and BCR repertoire when studying T cells and B cells, respectively. Immune repertoire refers to all of the unique T-cell receptor (TCR) and B-cell receptor (BCR) genetic rearrangements within the adaptive immune system. Through a mechanism called V(D)J recombination, irreversible somatic DNA recombination of these genetic regions during cellular development results in a mature lymphocyte having a single specificity. This means the adaptive immune system is capable of creating an immunological memory once someone is exposed to an infection, resulting in a more efficient and stronger response to future exposures.Įach unique antigen receptor only recognizes a single antigen and, incredibly, this range of specificity is encoded by a fixed number of gene segments. These lymphocytes have unique antigen receptors acquired through encounters with foreign bodies over a person’s lifetime. The more complex adaptive immune system takes days to respond to an infection and is composed of two major types of lymphocytes called B cells and T cells. The rapid response of your innate immune system also activates the adaptive system, which is the body’s antigen specific response to protect itself. Innate immunity refers to the non-specific defense mechanism that protects the body from a toxin or a foreign object, called an antigen. Your immune system is comprised of two subsystems that work together, providing both innate and adaptive immunity. ![]() ![]() ![]() Color display iPods then adopted some Mac OS X themes like Aqua progress bars, and brushed metal meant to evoke a combination lock. Later iPods switched fonts again to Podium Sans-a font similar to Apple's corporate font, Myriad. Starting with the iPod Mini, the Chicago font was replaced with Espy Sans. As development progressed, Apple continued to refine the software's look and feel, rewriting much of the code. Apple contracted another company, Pixo, to help design and implement the user interface (as well as Unicode, memory management, and event processing ) under the direct supervision of Steve Jobs. PortalPlayer had previously been working on an IBM-branded MP3 player with Bluetooth headphones. The platform had rudimentary software running on a commercial microkernel embedded operating system, licensed from Quadros. The iPod OS was developed on PCs using ARM development kits, and was written in C++. Jobs announced it as a Mac-compatible product with a 5 GB hard drive that put "1,000 songs in your pocket." Īpple did not develop the iPod software - sometimes called iPod OS - entirely in-house instead it purchased a reference platform from PortalPlayer, based on two ARM cores and used by the iPod to manage disk drivers, power management, and the real-time microkernel. The product ("the Walkman of the twenty-first century" ) was developed in less than one year and unveiled on October 23, 2001. The aesthetic was inspired by the 1958 Braun T3 transistor radio designed by Dieter Rams, while the wheel-based user interface was prompted by Bang & Olufsen's BeoCom 6000 telephone. Rubinstein had already discovered the Toshiba hard disk drive while meeting with an Apple supplier in Japan, and purchased the rights to it for Apple, and had also already worked out how the screen, battery, and other key elements would work. As ordered by CEO Steve Jobs, Apple's hardware engineering chief Jon Rubinstein assembled a team of engineers to design the iPod line, including hardware engineers Tony Fadell and Michael Dhuey, and design engineer Jonathan Ive. Digital cameras, camcorders, and organizers had well-established mainstream markets, but the company found existing digital music players "big and clunky or small and useless" with user interfaces that were "unbelievably awful," so Apple decided to develop its own. The iPod line came from Apple's "digital hub" category, when the company began creating software for the growing market of personal digital devices. ![]() Following the lackluster sales of these devices, Apple wanted a mobile device and so started to develop a personal media player, which would become the iPod. Īpple made the Newton from 1993 to 1998 and made the eMate from 1997 to 1998. Apple announced on that the iPod product line would be retired once the last remaining inventory of the 7th-generation iPod touches are sold out. By 2020, only the iPod touch (7th generation) remained in production. During the middle of 2010, iPhone sales overtook those of the iPod. While the iPhone and iPad have essentially the same media player capabilities as the iPod line, they are generally treated as separate products. As of iOS 5, separate apps named "Music" and "Videos" are standardized across all iOS-powered products. īefore the release of iOS 5, the iPod branding was used for the media player included with the iPhone and iPad, a combination of the Music and Videos apps on the iPod touch. Prior to macOS 10.15, Apple's iTunes software (and other alternative software) could be used to transfer music, photos, videos, games, contact information, e-mail settings, Web bookmarks, and calendars to the devices supporting these features from computers using certain versions of Apple macOS and Microsoft Windows operating systems. ![]() Like other digital music players, some versions of the iPod can serve as external data storage devices. The first version was released on October 23, 2001, about 8½ months after the Macintosh version of iTunes was released. The iPod was a line of portable media players and multi-purpose pocket computers designed and marketed by Apple Inc. For a specific product, see list of iPod models.Īn iPod shuffle, nano, classic, and touch. This article is about the series of media players. (Contains excessive redlinks that should be resolved to Wikipedia or a potential article in this wiki.) ![]() This article may require cleanup to meet this Wiki's standards. ![]() ![]() Surf the Internet while you listen to music, check your email and social networking accounts, watch streaming videos, write a paper, work on a presentation, or whatever else you can imagine! Now with one simple cable connection to your computer, you can access to large screen displays, stereo speakers, external hard drive, optical drive, printer, full-size keyboard and mouse. Installing random drivers could cause problems.Įxport Control and EULA Use of any software made available for download from this system constitutes your acceptance of the Export Control Terms and the terms in the Dynabook end-user license agreement both of which you can view before downloading any such software.Expand your computer’s potential with the dynadock® U3.0, the universal docking station that links all your electronic devices to your laptop with just one single USB 3.0 cable. If everything’s working correctly, you most likely shouldn’t worry about it.If “ Unknown device” is listed under “ Other devices” Drivers: For most cases, use “Toshiba Web Camera Application.".Download “Bluetooth Stack” and the Bluetooth driver corresponding to that brand.Use the network or other filter and OS filter on the Drivers & Updates page.Find wireless card brand as described above in the Wireless Drivers section.Follow the directions for Ethernet / LAN above but dismiss adapters that mention “VPN,” “Debug” and “Ethernet.” It may say “Wireless.” Use the " Wi-Fi filter instead of "LAN.".Download the top-most driver that mentions the brand you found earlier. ![]() Use “ LAN” filter and OS filter on the Drivers & Updates page.(If you are unable to determine which entry of multiple is applicable but they’re both the same brand, you don’t actually need to determine which entry is applicable.) Most likely it’s Intel, Broadcom, Atheros, or Realtek. Look for a network adapter that does not mention “VPN,” “Debug,” or “Wireless.” It may include the word “Ethernet.” Note the brand.Note that “ Wireless display driver” is not the standard display driver.Pick the top-most graphics driver that mentions your display brand (Intel, nVidia, AMD).Select the Display filter and your OS filter on the Drivers & Updates page.Check the detailed specifications on your product's support page to see if you have Intel, nVidia, or AMD graphics.(For example, if the problem is with graphics, select "Display.") Pick the filter corresponding to that device on the Drivers & Updates page.If you are having a problem with a specific piece of hardware: While continuing to hold the Windows key, press the 'x' key to open a menu in the lower-left.Device Manager window will open and look similar to below.Select " Device Manager" from the search results.Type " Device Manager" in the Start Menu's search field.To learn how to open device manager locate your OS below for the steps to open device manager ![]() ![]() The illustration below shows an example of how we can use device manager to discover that the audio card manufacturer is Conexant. To find the correct driver for the hardware installed in you computer sometimes it will be neccessary to discover what the hardware manufacturer name is. Opening Device Manager to find device hardware names
![]() Of course, WinRAR can be used to compress files into many other compressed formats, and the program benefits from the fact that it is available for just about every platform imaginable. This exclusivity comes at a price that is similar to WinZip. Most compression programs can extract RAR archives, but only WinRAR can (officially) create them. WinZip is an incredibly useful tool to have in your software arsenal, and it's flexible enough to work in the way that suits you best – you can create and extract via the program interface, or using the program window.Īnd if you'd rather not pay money, we've featured the best free alternatives to Winzip.Īs famous as WinZip in certain circles, WinRAR created a name for itself thanks to its proprietary RAR format, which offers incredible levels of compression. The interface adapts to suit mouse and keyboard setups or touchscreen devices, and there are backup and security options thrown in to protect your files. Other bonus features include the splitting of large zip files to fit different media, advanced file sharing options, cloud support and an advanced zip management system that rivals Windows Explorer. In addition to support for a wide range of archive formats (including ZIP, ZIPX, RAR (extraction only), 7z, TAR, GZIP, VHD and XZ), WinZip offers integration with a number of programs including Office for easy zipping as you work. Ultimately it depends on your priorities, but you do get a lot of extras for your money. However, you may wonder if you can justify spending money on a compression tool when there are so many free alternatives available. ![]() ![]() One of the most famous names in the world of software utilities, WinZip is still going strong after nearly 30 years, and is still one of the best file compression tools around. ![]() ![]() ![]() How To Convert a YouTube Video to MP3 file? I conducted the tests on my 8GB RAM Windows 11 PC. I’ve considered factors like conversion speed, video quality, resolution, support for various formats, and much more. This list is a blend of both web apps and downloadable software. I have spent hours testing 14 popular tools and singled out 10 options that performed the best. Get EaseUS Video Downloader How I Chose the Best YouTube to MP3 Converter for Windows? Batch download feature isn’t available in the free trial.Built-in search bar to directly look for YouTube videos.Built-in YouTube video-to-mp3 converter.Supports video downloads from any social media site. ![]() However, its paid version is capable of directly downloading YouTube playlists, or channels and videos in 4K/HD resolution.Īdditionally, it supports batch downloads. With its free trial, you can download only 2 videos. Moreover, the software supports downloading videos from other video streaming sites such as Facebook, TikTok, Instagram, etc. It can download YouTube videos in any format you wish. If you’re looking for a suitable converter for Windows and Android devices, you should consider EaseUs Video Downloader. EaseUS Video Downloader – Premium YouTube to MP3 Converter Its GPU acceleration feature makes conversion even faster.ĭownload WinX HD Video Converter 10.You can directly share the outputs to social media like Instagram, YouTube, etc.,.Support for numerous video and audio formats.Reduce the file size by up to 90% without losing quality.However, you can try its free trial before making a purchase. The primary downside is that it’s paid software with no free version available. The tool also offers advanced features for video editing, resizing, compressing, and enhancing quality. After that, select the format and resolution and then “Ok”. Paste the link in the Video URL tab and click on the “Analyze” button. You’ll find the YouTube URL button on the top menu bar. WinX HD Video Converter is a powerful YouTube to MP3 converter with support for various formats. Y2mate – Most Popular YouTube to MP3 Converter Online Paid software, free version available with limitations.ġ. Best YouTube to MP3 Converter for Windows Softwareīoth free and paid versions are available Continue reading to find the most efficient YouTube video converters. Searching for the best YouTube to MP3 converter for Windows? Maybe you want to create an offline music playlist or listen to a podcast without the video taking up space on your hard drive.Įither way, I got you covered. ![]() ![]() TikTok’s community moved to police itself as the video circulated, issuing warnings to followers to stay vigilant for the clip, which begins by showing a man with long hair and a beard on the phone seated at a desk. That rule change was not enough to stop the user from live streaming his own death last month. After a gunman broadcast a mass shooting at a New Zealand mosque last year, Facebook disallowed previous platform rule breakers from using Facebook Live. Graphic scenes of violence, sometimes broadcast live, have plagued social networks over the years and no solution has proven effective at keeping those videos from an audience. The situation is a particularly disturbing strain of trolling, as surprising users of all ages with an extremely graphic video could result in very real mental health consequences for anyone who ends up viewing it. ![]() The company expressed appreciation for community members taking action to report it and spread the word and reminded users that mental health hotlines are available within the app and the company’s safety hub. TikTok will ban any account that makes multiple attempts to upload the clip. “Our systems, together with our moderation teams, have been detecting and removing these clips for violating our policies against content that displays, praises, glorifies, or promotes suicide.” “On Sunday night, clips of a suicide that had originally been livestreamed on Facebook circulated on other platforms, including TikTok,” a TikTok spokesperson said in a statement. On TikTok, the For You page serves as the front page of the app, feeding users a stream of content tailored just for them. ![]() While the video first made the jump from Facebook in full, some TikTok users have now spliced it into unrelated videos so that other people view the clip without intending to when it pops up on the “For You” page. Originating on Facebook Live, the clip was uploaded onto TikTok over the weekend and began to take root in users’ algorithmic recommendations. ![]() A graphic video of a man committing suicide spread across TikTok early this week, and the company is still working to remove it. ![]() ![]() ![]() ![]() "This is a classic case of human trafficking where these defendants allegedly trapped an underage girl in dehumanizing circumstances in which they gave her drugs and forced her to have sex with multiple men per day,” New Jersey Attorney General Christopher Porrino said in a statement. The victim ultimately fled while White and Regn were asleep and contacted authorities. The victim did not receive money.ĭuring a three- or four-day stay at a motel in Wrightstown, White and Regn allegedly made the victim have sex with at least five men each day. ![]() White and Regn, who would stay in the same room as the victim or an adjoining room, would arrange for clients to meet the victim for sex and then collected all of the money paid by the clients, the indictment alleges. White and Regn allegedly placed a number of ads on with photos of the victim in various states of undress, including completely nude, advertising the girl’s services as an escort, according to prosecutors. White allegedly threatened to beat the victim if she did not take crystal meth, and he also allegedly threatened to find her and beat her if she did not continue to work for them as a prostitute. They allegedly said that if she did not work for them, it would be her fault if Regn’s children ended up on the street. Major flooding concerns persist in NJ with Friday storm ahead, potential snow next week Top News Photos: Pope Visits Japan, and More Instead, White and Regn allegedly gave her drugs, including crystal methamphetamine and marijuana, and told her that she needed to work as an “escort” for them so that they could make money. Regn has two young children, and the victim, who knew White, went to the first motel believing she would be babysitting the children, prosecutors said. The investigation began after the victim reported she was forced by White and Regn to work as a prostitute at various hotels where the defendants lived in Burlington County for a period of 10 days in October 2016. Prosecutors say the couple has been held in the Burlington County jail since their arrests in May. A man and his girlfriend have been indicted on charges of human trafficking of a minor and other crimes in connection with the caseĪ 19-year-old New Jersey man and his 28-year-old girlfriend have been indicted for allegedly forcing a 17-year-old girl into prostitution at local motels, where she was sometimes made to sleep with up to five men a day, and snort crystal methamphetamine, the state attorney general's office said Tuesday.Ī state grand jury indicted Christopher White, of Eastampton, and Adria Regn, of Mount Holly, Monday on charges of conspiracy, human trafficking of a minor, promoting prostitution of a minor and offenses related to child pornography and other crimes.She had to sleep with up to five men a day during three- or four-night stays at NJ motels she escaped after 10 days of the nightmare.The victim thought she was going to babysit one of the defendants' kids and was forced to become a prostitute, officials say. ![]() ![]() ![]() The free one has the following limitations: It offers free and premium ($6.25/month, billed annually) accounts. To use it, you need to register or sign in with Facebook. Picovico is another online tool to turn photos into videos. Verdict: Slydely is perfect slideshow creator for fast work and sharing online. only one default template for slideshows.image upload from multiple social accounts.Moreover, on this website you may follow other people and borrow their slideshow ideas. You may keep it in your account, share with Slidely community or record the slideshow from your PC screen. Unfortunately, there is no slideshow download option. add title, description, tags for your slideshow, make it public or private.add a music file or choose among available tracks.upload your photos or add them from your social media accounts.Slydely is a free online app for slideshow creation and sharing. Even a trial account lets work miracles with your photos.Īnimoto for Education: Simple Video Maker for Schools Slydely Verdict: Animoto is great for professional use. all unfinished videos are saved in your account.possibility to add call-to-action and your own logo.dozens of professionally designed templates.once the slideshow is ready, click Produce and share or download the video in the quality you need.Įven with a trial account, you’ll be able to download the resulted video to PC, upload to YouTube or share via email.edit the slideshow (change a song, arrange photos, add a logo). ![]() To make a slideshow in Animoto, follow the steps: The plans depend on your needs: $8/month (billed annually) for personal use with Animoto logo on output $22 and $34/month for professional use with more advanced options. Then you’ll have to upgrade or register another trial account. It provides a free 14-day trial period of PRO account. SEE ALSO: 5 Best Invitation Makers to Send Online and Paper Invites AnimotoĪnimoto is an online photo slideshow maker. Still the templates are more than fabulous. If you just need a single slideshow, it’s not worth paying or trying getarounds to get the video. Verdict: Smilebox is a perfect choice for a regular use. Tip! If you don’t want to upgrade to save the slideshow as a video, you may screencast the preview with the help of these free tools. add text, music, background if necessary.transfer photos to slides or let the tool auto-fill them.To create a slideshow in Smilebox, you need: With it, it’ll be able to use any of 1,200 premium templates and save your slideshow in video or DVD format. To get most of it, you have to sign up and buy Club Smilebox subscription for $3.99/month. Smilebox is another Windows tool for making collages, ecards, invitations, etc. ![]() SEE ALSO: Where to Get Music for your Slideshows Smilebox It’s also the best option for slideshows containing a large number of pictures. Verdict: Freemake Video Converter is ideal for quick slideshow making when you just need to arrange your photos into a video steam. possibility to write slideshows onto a DVD with DVD burner software.option to add DVD parts using DVD Ripper into the slideshow. ![]() If you want to mix photos and videos, don’t forget to turn on video join option. SEE ALSO: How to Create Photo Slideshow with Music Free
![]() wave drag ( aerodynamics) is caused by the presence of shockwaves and first appears at subsonic aircraft speeds when local flow velocities become supersonic.lift-induced drag appears with wings or a lifting body in aviation and with semi-planing or planing hulls for watercraft.For example, the Douglas DC-3 has an equivalent parasite area of 23.7 sq ft and the McDonnell Douglas DC-9, with 30 years of advancement in aircraft design, an area of 20.6 sq ft although it carried five times as many passengers. It is used for comparing the drag of different aircraft. Parasite drag is often expressed in terms of a hypothetical (in so far as there is no edge spillage drag ) "equivalent parasite drag area" which is the area of a flat plate perpendicular to the flow. For aircraft, pressure and friction drag are included in the definition of parasitic drag. A body is known as bluff (or blunt) if the source of drag is dominated by pressure forces and streamlined if the drag is dominated by viscous forces. ![]() Also shown is a flat plate illustrating the effect that orientation has on the relative proportions of skin friction and pressure difference between front and back. The effect of streamlining on the relative proportions of skin friction and form drag is shown for two different body sections, an airfoil, which is a streamlined body, and a cylinder, which is a bluff body.
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